Zip Codes

From Biowiki
Revision as of 23:43, 1 January 2017 by Move page script (talk | contribs) (Move page script moved page ZipCodes to Zip Codes: Rename from TWiki to MediaWiki style)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search

Zip Codes are cis acting post-transcriptional regulatory motifs, often found e.g. in 3'UTRs, that direct the localization of mRNAs.

An example is the Translational Control Element (TCE) found in the 3'UTR of nanos, which establishes a posterior-anterior axis during development of fruitfly oocytes (proto-eggs). This localization of the transcript is achieved via complementary, redundant mechanisms of selective degradation and transport.

-- Ian Holmes - 03 Apr 2005