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Human Coronavirus OC43

Click here to view the JBrowse genome annotation for HCoV-OC43!
OMGBrowse site for HCoV-OC43

Table of Contents:


  • A member of Coronaviridae.
  • Host: Human
  • NCBI Reference sequence: NC_005147.1
  • Genome length: 31,357 nt
  • ssRNA, (+) strand, linear
  • Non-segmented
  • 10 genes
  • GC content: 36.9%

A brief history

Human coronavirus OC43, or HCoV-OC43, was first isolated in 1967 from volunteers at the Common Cold Unit in Salisbury, United Kingdom. Together with HCoV-229E, HCoV-OC43 causes 10-30% of all common colds.


Group Group IV (Wikipedia:Positive-sense_ssRNA_virus#Group_IV_-_positive-sense_ssRNA_viruses)
Order Nidovirales (Wikipedia:Nidovirales)
Family Coronaviridae (Wikipedia:Coronaviridae)
Genera Coronavirus (Wikipedia:Coronavirus)


Coronaviruses are enveloped, (+)ssRNA viruses which infect animals. Commonly they infect the upper respiratory or GI tract. They are responsible for diseases including the common cold and SARS. The 5'-end of the genome has a methylated cap and the 3'-end has a poly (A) tract, mimicking host mRNA. Host ribosomes readily attach to the viral genome and initiate translation.


-- ArthurYu - 11 Dec 2009

I Attachment Action Size Date Who Comment
Zipzip ayu-be131-fa09-finalproj.zip manage 815.6 K 2009-12-11 - 12:34 ArthurYu arthur yu's final project for be131-fa09
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