Mercator files specify an orthology map between multiple genomes: a symmetric, 1-to-1 mapping between regions in different genomes.
The Mercator program creates this map by extending cliques of orthologous exons into syntenic runs.
Local alignment programs (PECAN, MAVID, FSA) are typically then run on each syntenic region, producing an alignment for each line in the Mercator map file.
Two files are actually needed:
map (containing the co-ordinates) and
genomes (specifying the order of genomes in
- Mercator program by ColinDewey
- Format of the
- References for Mercator: